Salesforce is the number one CRM platform in the world. Its software is cloud-based, which is why an expert IT team isn't needed to configure or manage it. Just log into your session and you're good to go.
Many businesses wish they could develop information systems which consume and modify Salesforce data. Although this may seem like too complex a task, Salesforce does offer a REST or SOAP API which allows you to interact with said CRM. This API lets you consume the data from Salesforce and then display them through a new user interface on your system. It also makes it possible to save and update information inside the CRM's database.